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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
9.09
Human Site:
T434
Identified Species:
18.18
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
T434
H
M
R
G
R
S
I
T
N
D
S
A
V
L
S
Chimpanzee
Pan troglodytes
XP_511742
777
85768
T434
H
M
R
G
R
S
I
T
N
D
S
A
V
L
S
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
T434
H
M
R
G
R
S
I
T
N
D
S
A
V
L
S
Dog
Lupus familis
XP_540486
782
86005
N438
V
R
G
R
S
I
T
N
D
S
A
V
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
D434
R
G
R
S
I
T
N
D
S
A
V
L
S
L
F
Rat
Rattus norvegicus
Q9JJ50
776
86228
N434
M
R
G
R
S
I
T
N
D
S
A
V
L
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
L434
H
P
Q
L
L
E
M
L
N
Q
L
D
E
R
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
D432
S
Y
I
K
E
M
D
D
K
R
M
W
Y
E
Q
Honey Bee
Apis mellifera
XP_393989
830
92147
E433
R
L
L
R
Y
I
Q
E
Q
D
D
S
R
V
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
A431
K
L
A
Q
I
R
D
A
R
E
A
L
D
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
Q336
A
S
R
Q
M
Q
P
Q
Q
P
S
P
Q
P
Q
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
D431
S
K
H
D
T
L
L
D
L
H
A
K
L
S
T
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
100
100
0
N.A.
13.3
0
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
26.6
20
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
0
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
9
0
9
34
25
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
17
25
17
34
9
9
9
0
0
% D
% Glu:
0
0
0
0
9
9
0
9
0
9
0
0
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
9
17
25
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
34
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
0
17
25
25
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
9
0
0
0
0
9
0
0
9
0
0
0
% K
% Leu:
0
17
9
9
9
9
9
9
9
0
9
17
25
34
25
% L
% Met:
9
25
0
0
9
9
9
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
17
34
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
9
0
0
9
0
9
0
9
0
% P
% Gln:
0
0
9
17
0
9
9
9
17
9
0
0
9
0
17
% Q
% Arg:
17
17
42
25
25
9
0
0
9
9
0
0
9
9
9
% R
% Ser:
17
9
0
9
17
25
0
0
9
17
34
9
9
25
25
% S
% Thr:
0
0
0
0
9
9
17
25
0
0
0
0
0
0
9
% T
% Val:
9
0
0
0
0
0
0
0
0
0
9
17
25
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
9
0
0
9
0
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _